Altstadt (around Marienplatz)
Good for: First-timers, walking to sights
Marienplatz, the Frauenkirche, the Residenz and the Viktualienmarkt are all within walking distance. Hotels are pricey.
Maxvorstadt
Good for: Museums, university atmosphere
The university and museum quarter, full of cafés and bookshops, close to both the old town and the English Garden.
Schwabing
Good for: English Garden, cafés and walks
A lively neighborhood west of the English Garden with plenty of cafés and restaurants. The Lufthansa Express Bus stops at Munich North (Schwabing).
Haidhausen
Good for: Quiet streets, local feel
An old residential quarter east of the Isar with squares and small eateries, near Ostbahnhof on the S8.
Around Hauptbahnhof
Good for: Airport and rail links, day trips
The airport S-Bahn, the Lufthansa Express Bus and trains toward Füssen and Dachau leave from here, handy for day trips. Less atmospheric for sightseeing.